PDVer, a tool to verify PDDL planning domains.

We present a methodology and a tool for the problem of testing and verifying that a PDDL planning domain satisfies a set of requirements, a need that arises for instance in space missions. We first review and analyse coverage conditions for requirement-based testing, and present how test cases can be derived automatically from requirements. Additionally, we show how test cases can be translated into additional planning goals. To automate this process, we introduce PDVer, an Eclipse plug-in for the automatic generation of PDDL code from requirements expressed in LTL. We evaluate the effectiveness of our approach and the usability of our tool against the Rovers domain from the fifth International Planning Competition (IPC-5)

A formal analysis of requirements-based testing

The aim of requirements-based testing is to generate test cases from a set of requirements for a given system or piece of software. In this paper we propose a formal semantics for the generation of test cases from requirements by revising and extending the results presented in previous works (e.g.: [21, 20, 13]). We give a syntactic characterisation of our method, defined inductively over the syntax of LTL formulae, and prove that this characterisation is sound and complete, given some restrictions on the formulae that can be used to encode requirements. We provide various examples to show the applicability of our approach

Predicting pilot behavior in medium-scale scenarios using game theory and reinforcement learning

Cataloged from PDF version of article.A key element to meet the continuing growth in air traffic is the increased use of automation. Decision support systems, computer-based information acquisition, trajectory planning systems, high-level graphic display systems, and all advisory systems are considered to be automation components related to next generation (NextGen) air space. Given a set of goals represented as reward functions, the actions of the players may be predicted. However, several challenges need to be overcome. First, determining how a player can attempt to maximize their reward function can be a difficult inverse problem. Second, players may not be able to perfectly maximize their reward functions. ADS-B technology can provide pilots the information, position, velocity, etc. of other aircraft. However, a pilot has limited ability to use all this information for his/her decision making. For this scenario, the authors model these pilot limitations by assuming that pilots can observe a limited section of the grid in front of them

Assessment of synergistic effect on performing the co-pyrolysis process of coal and waste blends based on thermal analysis

The preliminary thermogravimetric studies of co-pyrolyzed low rank coals (lignites Kostolac and Kolubara) with waste materials (spent coffee ground and waste rubber granulate) in a form of blends have been performed. Thermal analysis measurements of blend samples were carried out in a nitrogen, atmosphere at three different heating rates of 10, 15, and 20 K per minute. The coal-waste blends were prepared in the percentage ratios of 90:10, 80:20, and 70:30. This work analyzed the synergy analysis for considered blends shown via descriptive parameters during co-pyrolysis process. According to the performed analysis, the presence of synergistic effect was identified, where strong interactions were also observed. For lignite-spent coffee ground blends, it was found that two factors which affect the synergy effect with coal are concentration of added biomass material and the heating rate. For lignite-tire rubber granulate blends, the blending ratio take on a decisive role for positive consequences of a synergistic effect (ratios below 30% of tire rubber granulate in coals are desirable). Also, in this work the influence of micro-scale condition parameters such as heating rate (as the experimental regulatory factor) was analyzed on the magnitude response of synergism during co-pyrolysis

Type Inference for Deadlock Detection in a Multithreaded Polymorphic Typed Assembly Language

We previously developed a polymorphic type system and a type checker for a multithreaded lock-based polymorphic typed assembly language (MIL) that ensures that well-typed programs do not encounter race conditions. This paper extends such work by taking into consideration deadlocks. The extended type system verifies that locks are acquired in the proper order. Towards this end we require a language with annotations that specify the locking order. Rather than asking the programmer (or the compiler's backend) to specifically annotate each newly introduced lock, we present an algorithm to infer the annotations. The result is a type checker whose input language is non-decorated as before, but that further checks that programs are exempt from deadlocks

Effects of Oxygen During Long-term Hypothermic Machine Perfusion in a Porcine Model of Kidney Donation After Circulatory Death

International audienceBackground:Hypothermic machine perfusion (HMP) has become standard care in many center’s to preserve kidneys donated after circulatory death (DCD). Despite a significant reduction in metabolism at low temperatures, remaining cellular activity requires oxygen. Since the role and safety of oxygen during HMP has not been fully clarified, its supply during HMP is not standard yet. This study investigates the effect of administering oxygen during HMP on renal function in a porcine DCD model.Methods: After 30 minutes of warm ischemia, porcine slaughterhouse kidneys were preserved for 24 hours by means of cold storage (CS), or HMP with Belzer Machine Perfusion Solution (UW- MPS) supplemented with no oxygen, 21% or 100% oxygen. Next, kidneys were reperfused for 4 hours in a normothermic machine perfusion (NMP) setup.Results:HMP resulted in significantly better kidney function during NMP. Thiobarbituric acid-reactive substances (TBARS), markers of oxidative stress, were significantly lower in HMP preserved kidneys. HMP preserved kidneys showed significantly lower ASAT and LDH levels compared to kidneys preserved by CS. No differences were found between the HMP groups subjected to different oxygen concentrations. ATP levels significantly improved during HMP when active oxygenation was applied.Conclusion:This study showed that preservation of DCD kidneys with HMP is superior to CS. Although the addition of oxygen to HMP did not result in significantly improved renal function, beneficial effects were found in terms of reduced oxidative stress and energy status. Oxygen addition proofed to be safe and did not show detrimental effects

The unusual 2006 dwarf nova outburst of GK Perseii

The 2006 outburst of GK Perseii differed significantly at optical and ultraviolet wavelengths from typical outbursts of this object. We present multi-wavelength (X-ray, UV and optical) Swift and AAVSO data, giving unprecedented broad-band coverage of the outburst, allowing us to follow the evolution of the longer-than-normal 2006 outburst across these wavelengths. In the optical and UV we see a triple-peaked morphology with maximum brightness ~1.5 magnitudes lower than in previous years. In contrast, the peak hard X-ray flux is the same as in previous outbursts. We resolve this dichotomy by demonstrating that the hard X-ray flux only accounts for a small fraction of the total energy liberated during accretion, and interpret the optical/UV outburst profile as arising from a series of heating and cooling waves traversing the disc, caused by its variable density profile.Comment: 9 pages, 7 figures, accepted for publication in MNRA

Potential of Donation After Unexpected Circulatory Death Programs Defined by Their Demographic Characteristics

BACKGROUND. Donation after unexpected circulatory death (uDCD) donors are often suggested to increase the number of donor organs. In 2014, a uDCD protocol was implemented in three transplant centers in the Netherlands which unfortunately did not result in additional transplantations. This study was initiated to identify demographic factors influencing the potential success of uDCD programs. METHODS. Dutch resuscitation databases covering various demographic regions were analyzed for potential donors. The databases were compared with the uDCD implementation project and successful uDCD programs in Spain, France, and Russia. RESULTS. The resuscitation databases showed that 61% of all resuscitated patients were transferred to an emergency department. Age selection reduced this uDCD potential to 46% with only patients aged 18–65 years deemed eligible. Of these patients, 27% died in the emergency department. The urban region of Amsterdam showed the largest potential in absolute numbers (52 patients/y). Comparison with the uDCD implementation project showed large similarities in the percentage of potential donors; however, in absolute numbers, it showed a much smaller potential. Calculation of the potential per million persons and the extrapolation of the potential based on the international experience revealed the largest potential in urban regions. CONCLUSIONS. Implementation of a uDCD program should not only be based on the number of potential donors calculated from resuscitation databases. They show promising potential uDCD percentages for large rural regions and small urban regions; however, actual numbers per hospital are low, leading to insufficient exposure rates. It is, therefore, recommendable to limit uDCD programs to large urban regions

Proteomic analysis of machine perfusion solution from brain dead donor kidneys reveals that elevated complement, cytoskeleton and lipid metabolism proteins are associated with 1-year outcome

Assessment of donor kidney quality is based on clinical scores or requires biopsies for histological assessment. Noninvasive strategies to identify and predict graft outcome at an early stage are, therefore, needed. We evaluated the perfusate of donation after brain death (DBD) kidneys during nonoxygenated hypothermic machine perfusion (HMP). In particular, we compared perfusate protein profiles of good outcome (GO) and suboptimal outcome (SO) 1-year post-transplantation. Samples taken 15 min after the start HMP (T1) and before the termination of HMP (T2) were analysed using quantitative liquid chromatography-tandem mass spectrometry (LC-MS/MS). Hierarchical clustering of the 100 most abundant proteins showed discrimination between grafts with a GO and SO at T1. Elevated levels of proteins involved in classical complement cascades at both T1 and T2 and a reduced abundance of lipid metabolism at T1 and of cytoskeletal proteins at T2 in GO versus SO was observed. ATP-citrate synthase and fatty acid-binding protein 5 (T1) and immunoglobulin heavy variable 2-26 and desmoplakin (T2) showed 91% and 86% predictive values, respectively, for transplant outcome. Taken together, DBD kidney HMP perfusate profiles can distinguish between outcome 1-year post-transplantation. Furthermore, it provides insights into mechanisms that could play a role in post-transplant outcomes.</p